Molecular biology of severe acute respiratory syndrome coronavirus : Host-microbe interactions: viruses
Identifieur interne : 005B08 ( Main/Exploration ); précédent : 005B07; suivant : 005B09Molecular biology of severe acute respiratory syndrome coronavirus : Host-microbe interactions: viruses
Auteurs : John Ziebuhr [Allemagne]Source :
- Current opinion in microbiology [ 1369-5274 ] ; 2004.
Descripteurs français
- KwdFr :
- ARN messager (métabolisme), ARN viral (métabolisme), Animaux, Biologie moléculaire, Génome viral, Humains, Lignée cellulaire, Protéines virales (génétique), Protéines virales (métabolisme), Réplication virale, Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (génétique), Virus du SRAS (métabolisme), Virus du SRAS (physiologie).
- MESH :
- génétique : Protéines virales, Virus du SRAS.
- métabolisme : ARN messager, ARN viral, Protéines virales, Virus du SRAS.
- physiologie : Virus du SRAS.
- virologie : Syndrome respiratoire aigu sévère.
- Pascal (Inist)
English descriptors
- KwdEn :
- Animals, Cell Line, Coronavirus, Genome, Viral, Humans, Molecular Biology, Molecular biology, Protein, RNA, RNA, Messenger (metabolism), RNA, Viral (metabolism), Replication, Review, SARS Virus (genetics), SARS Virus (metabolism), SARS Virus (physiology), Severe Acute Respiratory Syndrome (virology), Severe acute respiratory syndrome, Viral Proteins (genetics), Viral Proteins (metabolism), Virus Replication.
- MESH :
- chemical , genetics : Viral Proteins.
- chemical , metabolism : RNA, Messenger, RNA, Viral, Viral Proteins.
- genetics : SARS Virus.
- metabolism : SARS Virus.
- physiology : SARS Virus.
- virology : Severe Acute Respiratory Syndrome.
- Animals, Cell Line, Genome, Viral, Humans, Molecular Biology, Virus Replication.
Abstract
The worldwide epidemic of severe acute respiratory syndrome (SARS) in 2003 was caused by a novel coronavirus called SARS-CoV. Coronaviruses and their closest relatives possess extremely large plus-strand RNA genomes and employ unique mechanisms and enzymes in RNA synthesis that separate them from all other RNA viruses. The SARS epidemic prompted a variety of studies on multiple aspects of the coronavirus replication cycle, yielding both rapid identification of the entry mechanisms of SARS-CoV into host cells and valuable structural and functional information on SARS-CoV proteins. These recent advances in coronavirus research have important implications for the development of anti-SARS drugs and vaccines.
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Affiliations:
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Le document en format XML
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of severe acute respiratory syndrome coronavirus : Host-microbe interactions: viruses</title><author><name sortKey="Ziebuhr, John" sort="Ziebuhr, John" uniqKey="Ziebuhr J" first="John" last="Ziebuhr">John Ziebuhr</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Institute of Virology and Immunology, University of Würzburg, Versbacher Str. 7</s1><s2>97078 Würzburg</s2><s3>DEU</s3><sZ>1 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Basse-Franconie</region><settlement type="city">Wurtzbourg</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Current opinion in microbiology</title><title level="j" type="abbreviated">Curr. opin. microbiol.</title><idno type="ISSN">1369-5274</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Current opinion in 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Coronaviruses and their closest relatives possess extremely large plus-strand RNA genomes and employ unique mechanisms and enzymes in RNA synthesis that separate them from all other RNA viruses. The SARS epidemic prompted a variety of studies on multiple aspects of the coronavirus replication cycle, yielding both rapid identification of the entry mechanisms of SARS-CoV into host cells and valuable structural and functional information on SARS-CoV proteins. These recent advances in coronavirus research have important implications for the development of anti-SARS drugs and vaccines.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Bavière</li><li>District de Basse-Franconie</li></region><settlement><li>Wurtzbourg</li></settlement></list><tree><country name="Allemagne"><region name="Bavière"><name sortKey="Ziebuhr, John" sort="Ziebuhr, John" uniqKey="Ziebuhr J" first="John" last="Ziebuhr">John Ziebuhr</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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